Elsevier, a world-leading provider of scientific, technical and medical information products and services, and MPI Research, the largest single-site preclinical contract research organization worldwide, today announced the launch of A Comprehensive Guide to Toxicology in Preclinical Drug Development, a new reference work edited by Dr. Ali Said Faqi, Senior Director of Developmental and Reproductive Toxicology at MPI Research. The book will be featured at the Society of Toxicology's ToxExpo, March 10-14, 2013.
Addressing the unmet need for a detailed guide to preclinical toxicology research, the book guides scientists through the critically important and rapidly evolving process of answering the question: is a drug safe for patients? A Comprehensive Guide to Toxicology in Preclinical Drug Development is unique because it combines preclinical development for both small and large molecules and covers emerging technology and methods. For the first time, a reference brings this material together with information on vaccines, worldwide regulatory considerations (including Chinese regulations), and other emerging areas to help scientists understand and predict toxicity.
The book will benefit students as they begin work in preclinical environments in either private industry or academia. It also provides practicing toxicologists, new clinicians and regulatory professionals with a comprehensive reference manual on the practical aspects of preclinical work.
A Comprehensive Guide to Toxicology in Preclinical Drug Development, with contributions from 79 leading scientists, covers the latest in vitro, in vivo and technological advances in use today, from investigative toxicology to the evaluation of toxicity and pharmacologic effects of a new chemical entity. Chapter highlights include absorption, distribution, metabolism, excretion (ADME), acute sub-chronic and chronic toxicity testing, toxicogenomics, developmental and reproductive toxicology, carcinogenicity testing, histopathology, imaging, immunotoxicity, and other relevant topics.
The book, published by Elsevier under the Academic Press imprint, is available electronically and in print and can be purchased on the Elsevier Store, as well as on ScienceDirect.